Further Information
HTR1A, 5-hydroxytryptamine (serotonin) receptor 1A, 5-HT1A, 5HT1a, ADRB2RL1, ADRBRL1, 5-HT-1A, 5-HT1a receptor, 5-hydroxytryptamine receptor 1A, G protein coupled receptor, G-21, OTTHUMP00000221821, guanine nucleotide-binding regulatory protein-coupled receptor, serotonin receptor 1A
Peptide ELISA: antibody detection limit dilution 1:16000.Western Blot:Preliminary experiments gave bands at approx 37kDa and 35kDa in Human Brain (Hippocampus, Substantia nigra) lysates after 0.1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 46.1kDa according to NP_000515.2. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands). We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20?C. Minimize freezing and thawing.
500 ug/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Expected Species Reactivity based on sequence homology: Human
The immunogen for this antibody is: C-QPKKSVNGESGSRN
3350
5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR1A
Homo sapiens
Liquid
NP_000515.2
55956923
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Signal Transduction ,Neuroscience ,Cancer
P08908