Antibody Clonality:
Polyclonal
Applications:- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store HTR3A antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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Further Information
HTR3A, HTR3, 5HT3R, 5-HT-3, 5-HT3A, 5-HT3R
HTR3A antibody can be used for detection of HTR3A by ELISA at 1:62500. HTR3A antibody can be used for detection of HTR3A by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
HTR3A belongs to the ligand-gated ion channel receptor superfamily. It is the subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.
- Panicker, S., et al., (2004) J. Biol. Chem. 279 (27), 28149-28158.
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
batch dependent
Unconjugated
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HTR3A.
3359
5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTR3A
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
55 kDa
NP_000860
253735700
Antibody is purified by peptide affinity chromatography method.
Membrane ,Cancer ,Signal Transduction
P46098
Optimal dilutions for each application to be determined by the researcher.