ProSci

SCN1B Antibody

Product Code:
 
PSI-25-240
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Canine (dog)
  • Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
For short periods of storage (days) store at 4˚C. For longer periods of storage, store SCN1B antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
1 / 1
Antibody used in WB on Human HeLa at 0.2-1 ug/ml.
❮❯

Antibody used in WB on Human HeLa at 0.2-1 ug/ml.

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PSI-25-240-100ul100ul£662.00
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Further Information

Additional Names:
SCN1B, GEFSP1, ATFB13, BRGDA5
Application Note:
SCN1B antibody can be used for detection of SCN1B by ELISA at 1:62500. SCN1B antibody can be used for detection of SCN1B by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
Voltage-gated sodium channels are essential for the generation and propagation of action potentials in striated muscle and neuronal tissues. Biochemically, they consist of a large alpha subunit and 1 or 2 smaller beta subunits, such as SCN1B. The alpha subunit alone can exhibit all the functional attributes of a voltage-gated Na+ channel, but requires a beta-1 subunit for normal inactivation kinetics.Voltage-gated sodium channels are essential for the generation and propagation of action potentials in striated muscle and neuronal tissues. Biochemically, they consist of a large alpha subunit and 1 or 2 smaller beta subunits, such as SCN1B. The alpha subunit alone can exhibit all the functional attributes of a voltage-gated Na+ channel, but requires a beta-1 subunit for normal inactivation kinetics.
Background References:
  • Selmer, K.K., (2008) Acta Neurol. Scand. 117 (4), 289-292.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SCN1B.
NCBI Gene ID #:
6324
NCBI Official Name:
sodium channel, voltage-gated, type I, beta subunit
NCBI Official Symbol:
SCN1B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
25 kDa
Protein Accession #:
NP_001028
Protein GI Number:
4506805
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Membrane ,Signal Transduction
Swissprot #:
Q07699
User NOte:
Optimal dilutions for each application to be determined by the researcher.