ProSci

TNFSF12 Antibody

Product Code:
 
PSI-31-142
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
For short periods of storage (days) store at 4˚C. For longer periods of storage, store TNFSF12 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
1 / 1
Antibody used in WB on Human Muscle at 0.2-1 ug/ml.
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Antibody used in WB on Human Muscle at 0.2-1 ug/ml.

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PSI-31-142-100ul100ul£662.00
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Further Information

Additional Names:
TNFSF12, APO3L, DR3LG, TWEAK
Application Note:
TNFSF12 antibody can be used for detection of TNFSF12 by ELISA at 1:12500. TNFSF12 antibody can be used for detection of TNFSF12 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Background References:
  • Jin, L., et al., (2004) J. Invest. Dermatol. 122 (5), 1175-1179.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TNFSF12.
NCBI Gene ID #:
8742
NCBI Official Name:
tumor necrosis factor (ligand) superfamily, member 12
NCBI Official Symbol:
TNFSF12
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
27 kDa, 37 kDa
Protein Accession #:
NP_003800
Protein GI Number:
4507597
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Transcription ,Cancer
Swissprot #:
O43508
User NOte:
Optimal dilutions for each application to be determined by the researcher.