Further Information
RPS6KB1, p70-S6K, ribosomal protein S6 kinase, 70kD, polypeptide 1, PS6K, S6K, S6K1, STK14A, p70(S6K)-alpha, p70-alpha, p70 S6 kinase, alpha 1, p70 S6 kinase, alpha 2, ribosomal protein S6 kinase, 70kD, polypeptide 1, serine/threonine kinase 14 alpha
Peptide ELISA: antibody detection limit dilution 1:8000.Western Blot:Approx 65kDa band observed in lysates of Human Placenta, of Rat Brain and of cell line NIH3T3 (calculated MW of 59.1kDa according to NP_003152.1). Recommended concentration: 0.05-0.1ug/ml.Immunohistochemistry:In paraffin embedded Human Kidney shows staining in the cytoplasm-rich PCT while less so in the DCT and no signals in the glomerulus. Recommended concentration: 2-4ug/ml.
- Grove JR, Banerjee P, Balasubramanyam A, Coffer PJ, Price DJ, Avruch J, Woodgett JR. Cloning and expression of two human p70 S6 kinase polypeptides differing only at their amino termini. Mol Cell Biol. 1991 Nov;11(11):5541-50.
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20?C. Minimize freezing and thawing.
500 ug/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Expected Species Reactivity based on sequence homology: Dog, Cow
The immunogen for this antibody is: C-MISKRPEHLRMNL
6198
ribosomal protein S6 kinase, 70kDa, polypeptide 1
RPS6KB1
Homo sapiens
Liquid
NP_003152.1
4506737
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Signal Transduction
.
P23443