Further Information
CDKN2A, cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) , HGNC:1787, ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, TP16, p14, p14ARF, p16, p16INK4, p16INK4a, p19 , CDK4 inhibitor p16-INK4, cell cycle negative regulator beta, cyclin-dependent kinase inhibitor 2A, cyclin-dependent kinase inhibitor 2A, p14ARF, cyclin-dependent kinase inhibitor p12, p16INK4a alternatively spliced form, cyclin-dependent kinase inhibitor p16, multiple tumor suppressor 1
Peptide ELISA: antibody detection limit dilution 1:128000.Western Blot:Approx 17kDa band observed in lysates of cell line HeLa (calculated MW of 12.1kDa according to NP_478104.1). Recommended concentration: 1-3ug/ml.
- Normand G, Hemmati PG, Verdoodt B, von Haefen C, Wendt J, Guner D, May E, Dorken B, Daniel PT. p14ARF induces G2 cell cycle arrest in p53- and p21-deficient cells by down-regulating p34cdc2 kinase activity. J Biol Chem. 2005 Feb 25;280(8):7118-30. Epub 2004 Dec 6.
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20?C. Minimize freezing and thawing.
500 ug/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
The immunogen for this antibody is: C-ILRKKGRLPGEFSE
1029
cyclin-dependent kinase inhibitor 2A
CDKN2A
Homo sapiens
Liquid
NP_478104.1
17738298
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Signal Transduction ,Homeostasis ,Cancer
This antibody is expected to recognize the pancreas isoform (NP_478104.1) only.
P42771