ProSci

Sufu Antibody

Product Code:
 
PSI-79-513
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store antibody at -20˚C for up to one year.
 

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CodeSizePrice
PSI-79-513-0.1mg0.1mg£488.00
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Further Information

Additional Names:
SUFUH, SUFUXL, PRO1280, CFL, SUFUH
Application Note:
Western Blot: 1:500~1:1000
Background:
SUFU encodes a component of the Sonic hedgehog (SHH; MIM 600725)/Patched (PTCH; MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes (e.g., HPE3, MIM 142945; BCNS, MIM 109400; and GCPS, MIM 175700)
Background References:
  • Zimmern P, et al. (2010) Neurourol Urodyn. 29 (5): 715-8. Wang C, et al. (2010) Development. 137 (12): 2001-9. Rabasseda X. et al. (2010) Drug News Perspect. 23 (4): 273-5.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Sufu (Phospho-Ser342) antibody was raised against a peptide sequence around phosphorylation site of Serine 342 (A-P-S (p) -R-K) derived from Human Sufu.
Modifications:
Phospho-Specific
NCBI Gene ID #:
51684
NCBI Official Name:
suppressor of fused homolog (Drosophila)
NCBI Official Symbol:
SUFU
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
54 kDa
Protein Accession #:
NP_057253.2
Protein GI Number:
19923479
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
This antibody detects endogenous level of Sufu protein only when phosphorylated at serine 342.
Swissprot #:
Q9UMX1