ProSci

E2F-2 Antibody

Product Code:
 
PSI-79-756
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store antibody at -20˚C for up to one year.
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Western blot analysis of lysed extracts from HeLa and K562 cells using E2F-2 Antibody.
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Western blot analysis of lysed extracts from HeLa and K562 cells using E2F-2 Antibody.

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PSI-79-756-0.1mg0.1mg£481.00
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Further Information

Additional Names:
E2F-2, HER2, MLN19, NEU, NGL, E2F-2
Application Note:
Western Blot: 1:500~1:1000
Background:
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from g1 to s phase. E2F-2 binds specifically to RB1 protein, in a cell-cycle dependent manner.
Background References:
  • Rubin S. M., Gall A. -L., Zheng N., Pavletich N. P. Cell 123:1093-1106 (2005)
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
E2F-2 antibody? was raised against a peptide sequence around aa.425~429 (L-F-D-S-Y) derived from Human E2F-2.
NCBI Gene ID #:
1870
NCBI Official Name:
E2F transcription factor 2
NCBI Official Symbol:
E2F2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
NP_004082.1
Protein GI Number:
4758226
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Cell Cycle
SPECIFICITY:
This antibody detects endogenous level of total E2F-2 protein.
Swissprot #:
Q14209