ProSci

CRY1 Antibody

Product Code:
 
PSI-79-637
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store antibody at -20˚C for up to one year.
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Western blot analysis of lysed extracts from mouse brain tissue using CRY1 Antibody.
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Western blot analysis of lysed extracts from mouse brain tissue using CRY1 Antibody.

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PSI-79-637-0.1mg0.1mg£481.00
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Further Information

Additional Names:
Phll1, AU020726, AU021000, PHLL1
Application Note:
Western Blot: 1:500~1:1000
Background:
Blue light-dependent regulator of the circadian feedback loop. Inhibits CLOCK|NPAS2-ARNTL E box-mediated transcription. Acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. Has no photolyase activity. Capable of translocating circadian clock core proteins such as PER proteins to the nucleus. May inhibit CLOCK|NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL
Background References:
  • Morioka N, et al. (2010) J Pharmacol Sci. 113 (3): 234-45. Fonseca F, et al. (2010) Mol Diagn Ther. 14 (3): 171-8. Stratmann M, et al. (2010) Genes Dev. 24 (12): 1317-28.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
CRY1 antibody was raised against a peptide sequence around aa.551~555 (S-Q-G-S-G) derived from Mouse CRY1.
NCBI Gene ID #:
12952
NCBI Official Name:
cryptochrome 1 (photolyase-like)
NCBI Official Symbol:
Cry1
NCBI Organism:
This antibody was raised against a peptide sequence around aa.551~555 (S-Q-G-S-G) derived from Mouse CRY1.
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
60 kDa
Protein Accession #:
NP_031797.1
Protein GI Number:
6681031
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Other
SPECIFICITY:
This antibody detects endogenous level of total CRY1 protein.
Swissprot #:
Q16526