ProSci

c-kit Antibody

Product Code:
 
PSI-79-430
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
 
Store antibody at -20˚C for up to one year.
1 / 2
Western blot analysis of lysed extracts from HL60 cells using c-kit (Ab-936).
2 / 2
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using c-kit (Ab-936).
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Western blot analysis of lysed extracts from HL60 cells using c-kit (Ab-936).
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using c-kit (Ab-936).

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PSI-79-430-0.1mg0.1mg£481.00
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Further Information

Additional Names:
PBT, SCFR, C-Kit, CD117, HSP27, HSP28, KIT, PBT
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Background:
This is the receptor for stem cell factor (mast cell growth factor). It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K)
Background References:
  • Martin, F. H. et al. (1990) Cell 63, 203-11. Blume-Jensen, P. et al. (2000) Nat Genet 24, 157-62. Gommerman, J. L. et al. (1997) J Biol Chem 272, 30519-25. Nocka, K. et al. (1990) EMBO J 9, 1805-13.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
c-kit (Ab-936) antibody was raised against a peptide sequence around aa.934~938 (H-I-Y-S-N) derived from Human c-Kit.
NCBI Gene ID #:
3815
NCBI Official Name:
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
NCBI Official Symbol:
KIT
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
145 kDa
Protein Accession #:
NP_000213.1
Protein GI Number:
4557695
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Other
SPECIFICITY:
This antibody detects endogenous level of total c-Kit protein.
Swissprot #:
P10721