ProSci

NAT2 Antibody

Product Code:
 
PSI-29-964
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
For short periods of storage (days) store at 4˚C. For longer periods of storage, store NAT2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
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Antibody used in WB.
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Antibody used in WB.

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PSI-29-964-100ul100ul£609.00
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Further Information

Additional Names:
NAT2, AAC2, PNAT, NAT-2
Application Note:
NAT2 antibody can be used for detection of NAT2 by ELISA at 1:312500. NAT2 antibody can be used for detection of NAT2 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
NAT2 is a N-acetyltransferase 2 (arylamine N-acetyltransferase 2). This enzyme functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in its gene are reponsible for the N-acetylation polymorphism in which human populations segregate into rapid,intermediate, and slow acetylator phenotypes. Polymorphisms in NAT2 are also associated with higher incidences of cancer and drug toxicity.This gene encodes N-acetyltransferase 2 (arylamine N-acetyltransferase 2). This enzyme functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are reponsible for the N-acetylation polymorphism in which human populations segregate into rapid,intermediate, and slow acetylator phenotypes. Polymorphisms in NAT2 are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near NAT2.
Background References:
  • Tamer, L., (2006) Cell Biochem. Funct. 24 (2), 131-135.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NAT2.
NCBI Gene ID #:
10
NCBI Official Name:
N-acetyltransferase 2 (arylamine N-acetyltransferase)
NCBI Official Symbol:
NAT2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
32 kDa
Protein Accession #:
NP_000006
Protein GI Number:
116295260
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Membrane ,Cancer
Swissprot #:
P11245
User NOte:
Optimal dilutions for each application to be determined by the researcher.