Further Information
MACS, 80K-L, PKCSL, PRKCSL, HSP27, HSP28, Protein kinase C substrate, 80 kDa protein, light chain
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein.
- Ramsden, J. J. (2000) Int. J. Biochem. Cell Biol. 32, 475-479. Graff, J. M. et al. (1989) J. Biol. Chem. 264, 21818-21823. Hartwig, J. H. et al. (1992) Nature 356, 618-622. Thelen, M. et al. (1991) Nature 351, 320-322.
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
1 mg/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
MARCKS (phospho-Ser170) antibody was raised against a peptide sequence around phosphorylation site of Serine 170 (G-F-S (p) -F-K) derived from Human MARCKS.
Phospho-Specific
4082
myristoylated alanine-rich protein kinase C substrate
MARCKS
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
80 kDa
NP_002347.5
153070260
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Phospho-Specific,Neuroscience
This antibody detects endogenous level of MARCKS only when phosphorylated at threonine 170.
P29966