Further Information
CBX1, HP1-BETA, chromobox homolog 1 (HP1 beta homolog Drosophila ), HGNC:1551, CBX, HP1Hs-beta, M31, MOD1, chromobox homolog 1 (Drosophila HP1 beta), heterochromatin protein p25 beta, HP1Hsbeta, p25beta, heterochromatin protein 1-beta, modifier 1 protein
Peptide ELISA: antibody detection limit dilution 1:32000.Western Blot:Approx. 25kDa band observed in lysates of A431, HeLa and HepG2 (calculated MW of 25kDa according to NP_006798.1). Recommended concentration: 0.3-1.0 ug/ml.Immunohistochemistry:In paraffin embedded Human Placenta shows strong nuclear staining in trophoblasts. Recommended concentration, 2-3ug/ml.
- Sharma GG, Hwang KK, Pandita RK, Gupta A, Dhar S, Parenteau J, Agarwal M, Worman HJ, Wellinger RJ, Pandita TK. Human heterochromatin protein 1 isoforms HP1(Hsalpha) and HP1(Hsbeta) interfere with hTERT-telomere interactions and correlate with changes in cell growth and response to ionizing radiation. Mol Cell Biol. 2003 Nov;23(22):8363-76.
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20?C. Minimize freezing and thawing.
500 ug/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog, Cow
The immunogen for this antibody is: C-QSQKTAHETDKSE
10951
chromobox homolog 1
CBX1
Homo sapiens
Liquid
NP_006798.1, NP_001120700.1
5803076
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Cancer
Variants (NP_006798.1; NP_001120700.1) encode the same protein.
P83916