Further Information
NR2C2, TAK1, TR2R1, TR4, hTAK1
NR2C2 antibody can be used for detection of NR2C2 by ELISA at 1:312500. NR2C2 antibody can be used for detection of NR2C2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes (Yoshikawa et al., 1996 [PubMed 8661150]).
- Bouwmeester, T., (2004) Nat. Cell Biol. 6 (2), 97-105.
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
batch dependent
Unconjugated
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR2C2.
7182
nuclear receptor subfamily 2, group C, member 2
NR2C2
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
67 kDa
NP_003289
36950991
Antibody is purified by peptide affinity chromatography method.
Transcription ,Signal Transduction ,Neuroscience
P49116
Optimal dilutions for each application to be determined by the researcher.