ProSci

TUG Monoclonal Antibody

Product Code:
 
PSI-32-195
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
4A11A6G11
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Mouse TUG monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis using Mouse TUG monoclonal antibody against NIH / 3T3 cell lysate.
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Western blot analysis using Mouse TUG monoclonal antibody against NIH / 3T3 cell lysate.

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PSI-32-195-0.1mL0.1mL£524.00
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Further Information

Additional Names:
ASPL, RCC17, TUG, UBXD9, UBXN9, Alveolar soft part sarcoma chromosomal region candidate gene 1 proteinTUG, ASPL, ASPS, ASPCR1
Application Note:
Western Blot:1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.
Background:
The TUG protein contains a UBX domain, for GLUT4. In truncated form, TUG acts in a dominant-negative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin.
Background References:
  • Nature 2003,425:727 - 733.
Buffer:
Purified antibody in PBS containing 0.03% sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Ni-NTA purified truncated recombinant TUG expressed in E. Coli strain BL21 (DE3).
NCBI Gene ID #:
79058
NCBI Official Name:
alveolar soft part sarcoma chromosome region, candidate 1
NCBI Official Symbol:
ASPSCR1
NCBI Organism:
Homo sapiens
Protein Accession #:
Q9BZE9
Protein GI Number:
74717746
Purification:
Antibody is purified by protein A affinity chromatography and resuspended in PBS with 0.2%BSA, 0.09% sodium azide.
Research Area:
Growth Factor
Swissprot #:
Q9BZE9
User NOte:
Optimal dilutions for each application to be determined by the researcher.