ProSci

SSX2 Antibody

Product Code:
 
PSI-28-727
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
For short periods of storage (days) store at 4˚C. For longer periods of storage, store SSX2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
1 / 1
Antibody used in WB on Human Jurkat 0.2-1 ug/ml.
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Antibody used in WB on Human Jurkat 0.2-1 ug/ml.

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PSI-28-727-100ul100ul£662.00
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Further Information

Additional Names:
SSX2, HD21, HOM-MEL-40, MGC119055, MGC15364, MGC3884, SSX, CT5.2, CT5.2A
Application Note:
SSX2 antibody can be used for detection of SSX2 by ELISA at 1:62500. SSX2 antibody can be used for detection of SSX2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
SSX2 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t (X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t (X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.
Background References:
  • Fernebro, J., (2006) Int. J. Cancer 118 (5), 1165-1172.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SSX2.
NCBI Gene ID #:
6757
NCBI Official Name:
synovial sarcoma, X breakpoint 2
NCBI Official Symbol:
SSX2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
25 kDa
Protein Accession #:
NP_003138
Protein GI Number:
27659724
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Transcription ,Cancer ,Signal Transduction
Swissprot #:
Q16385-2
User NOte:
Optimal dilutions for each application to be determined by the researcher.