ProSci

MXD4 Antibody

Product Code:
 
PSI-27-702
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
For short periods of storage (days) store at 4˚C. For longer periods of storage, store MXD4 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
1 / 1
Antibody used in WB on Human Jurkat 0.2-1 ug/ml.
❮❯

Antibody used in WB on Human Jurkat 0.2-1 ug/ml.

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PSI-27-702-100ul100ul£662.00
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Further Information

Additional Names:
MXD4, MAD4, MST149, MSTP149, bHLHc12
Application Note:
MXD4 antibody can be used for detection of MXD4 by ELISA at 1:12500. MXD4 antibody can be used for detection of MXD4 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
MXD4 is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.
Background References:
  • Jiang, D.J., et al., (2004) J. Biochem. Mol. Biol. 37 (4), 402-407.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MXD4.
NCBI Gene ID #:
10608
NCBI Official Name:
MAX dimerization protein 4
NCBI Official Symbol:
MXD4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
24 kDa
Protein Accession #:
NP_006445
Protein GI Number:
5453734
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Transcription ,Cancer
Swissprot #:
Q14582
User NOte:
Optimal dilutions for each application to be determined by the researcher.