ProSci

KHDRBS3 Antibody

Product Code:
 
PSI-29-385
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
 
For short periods of storage (days) store at 4˚C. For longer periods of storage, store KHDRBS3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
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Antibody used in WB on Human Jurkat 0.2-1 ug/ml.
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Antibody used in WB on Human Jurkat 0.2-1 ug/ml.

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PSI-29-385-100ul100ul£662.00
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This product comes from: United States.
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Further Information

Additional Names:
KHDRBS3, Etle, SALP, SLM2, SLM-2, TSTAR, T-STAR, etoile
Application Note:
KHDRBS3 antibody can be used for detection of KHDRBS3 by ELISA at 1:62500. KHDRBS3 antibody can be used for detection of KHDRBS3 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
As a RNA-binding protein, KHDRBS3 plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. KHDRBS3 may play a role as a negative regulator of cell growth. It inhibits cell proliferation and involved in splice site selection of vascular endothelial growth factor. It induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. It also involved in post-transcriptional regulation of HIV-1 gene expression.
Background References:
  • Cohen, C.D., (2005) J. Am. Soc. Nephrol. 16 (7), 1958-1965.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KHDRBS3.
NCBI Gene ID #:
10656
NCBI Official Name:
KH domain containing, RNA binding, signal transduction associated 3
NCBI Official Symbol:
KHDRBS3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
38 kDa
Protein Accession #:
NP_006549
Protein GI Number:
5730073
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
RNA Binding ,Cancer
Swissprot #:
O75525
User NOte:
Optimal dilutions for each application to be determined by the researcher.