Further Information
ERK2, PRKM1, PRKM2, Mitogen-activated protein kinase 1, ERT1, MAP kinase 1, ERK, p38, p40, p41, ERK2, ERK-2, MAPK2, P42MAPK, p41mapk, p42-MAPK
ERK2 antibody can be used for the detection of ERK2 by Western blot, may also work for IHC and ICC.
Mitogen-activated protein kinase 1; extracellular signal-regulated kinase 2; protein tyrosine kinase ERK2; mitogen-activated protein kinase 2. This protein is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
- Bhalla, U. S., Ram, P. T., Iyengar, R. MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network. Science 297: 1018-1023, 2002.
Phosphate-Buffered Saline. No preservatives added.
1 mg/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
232-360
5594
mitogen-activated protein kinase 1
MAPK1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
41.3 kDa (calculated)
NP_620407.1
20986531
Antigen affinity-purified
Signal Transduction, Cancer
P28482
Optimal dilutions for each application to be determined by the researcher.