ProSci

HDAC2 Antibody

Product Code:
 
PSI-79-335
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
 
Store antibody at -20˚C for up to one year.
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Western blot analysis of lysed extracts from 293 and HeLa cells using HDAC2 (Ab-394).
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<b>Top Image:</b> Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using HDAC2 (Ab-394).<b>Bottom Image:</b> Immunofluorescence staining of methanol-fixed HeLa cells using HDAC2 (Ab-394).
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Western blot analysis of lysed extracts from 293 and HeLa cells using HDAC2 (Ab-394).
<b>Top Image:</b> Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using HDAC2 (Ab-394).<b>Bottom Image:</b> Immunofluorescence staining of methanol-fixed HeLa cells using HDAC2 (Ab-394).

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PSI-79-335-0.1mg0.1mg£481.00
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Further Information

Additional Names:
HD2, RPD3, YAF1, SVP65, SYT, HD2, Histone deacetylase 2
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Background:
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes
Background References:
  • Tsai SC, et al. (2002) J Biol Chem; 277 (35): 31826-33
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
HDAC2 (Ab-394) antibody was raised against a peptide sequence around aa. 392~396 (E-D-S-G-D) derived from Human HDAC2.
NCBI Gene ID #:
3066
NCBI Official Name:
histone deacetylase 2
NCBI Official Symbol:
HDAC2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
60 kDa
Protein Accession #:
NP_001518.2
Protein GI Number:
116284376
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Cell Cycle
SPECIFICITY:
This antibody detects endogenous level of total HDAC2 protein.
Swissprot #:
Q92769