Antibody Clonality:
Polyclonal
Application:
Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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Further Information
ERBB, HER1, mENA, ERBB1, PIG61, Receptor protein-tyrosine kinase ErbB-1, kinase EGFR
Western Blot: 1:500~1:1000
Receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with SRC and CTNNB1/beta-catenin.
- Inoue A, et al. (2005) PLoS Med; 2 (1): e13Sun H, et al. (2004) EMBO J; 23 (1): 100-110Kanner SB, et al. (1991) Mol Cell Biol; 11 (2): 713-720Wu TT, et al. (1998) Mol Biol Cell; 9 (7): 1661-1674O?Rourke DM, et al. (1997) Proc Natl Acad Sci U S A; 94 (7): 3250-3255Goldstein DJ, et al. (1994) J Virol; 68 (7): 4432-4441
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
1 mg/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
EGFR (Phospho-Tyr869) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 869 (K-E-Y (p) -H-A) derived from Human EGFR.
Phospho-Specific
1956
epidermal growth factor receptor
EGFR
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
175 kDa
NP_005219.2
29725609
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Phospho-Specific
This antibody detects endogenous level of EGFR only when phosphorylated at tyrosine 869.
P00533