ProSci

CDC2 Antibody

Product Code:
 
PSI-79-559
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Western Blot (WB)
Storage:
 
Store antibody at -20˚C for up to one year.
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Western blot analysis of lysed extracts from COLO cells using CDC2 (Ab-161).
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Immunofluorescence staining of methanol-fixed HeLa cells using CDC2 (Ab-161).
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Western blot analysis of lysed extracts from COLO cells using CDC2 (Ab-161).
Immunofluorescence staining of methanol-fixed HeLa cells using CDC2 (Ab-161).

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PSI-79-559-0.1mg0.1mg£481.00
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Further Information

Additional Names:
CDC2, CDC28A, P34CDC2, CDC28, CDC2A, CDK1, Cyclin-dependent kinase 1
Application Note:
Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200
Background:
Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.
Background References:
  • Ukomadu C, et al. (2003) J Biol Chem; 278 (7): 4840-6Morris MC, et al. (2002) J Biol Chem; 277 (26): 23847-53Brown NR, et al. (1999) J Biol Chem; 274 (13): 8746-56Liu Y, et al. (2004) J Biol Chem; 279 (6): 4507-14
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
CDC2 (Ab-161) antibody was raised against a peptide sequence around aa.159~163 (T-Y-T-H-E) derived from Human CDC2.
NCBI Gene ID #:
983
NCBI Official Name:
cyclin-dependent kinase 1
NCBI Official Symbol:
CDK1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
34 kDa
Protein Accession #:
NP_001163877.1
Protein GI Number:
281427278
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Apoptosis,Cancer,Cell Cycle
SPECIFICITY:
This antibody detects endogenous level of total CDC2 protein.
Swissprot #:
P06493