ProSci

SLC26A3 Antibody

Product Code:
 
PSI-25-021
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
For short periods of storage (days) store at 4˚C. For longer periods of storage, store SLC26A3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
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Antibody used in WB on Human Placenta lysate at 0.2-1 ug/ml.
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Antibody used in WB on Human Placenta lysate at 0.2-1 ug/ml.

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PSI-25-021-100ul100ul£662.00
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Further Information

Additional Names:
SLC26A3, CLD, DRA
Application Note:
SLC26A3 antibody can be used for detection of SLC26A3 by ELISA at 1:312500. SLC26A3 antibody can be used for detection of SLC26A3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
SLC26A3 is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea.The protein encoded by this gene is a transmembrane glycoprotein that functions as a sulfate transporter. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. Mutations in this gene have been associated with congenital chloride diarrhea. Please see the Entrez Gene record to access additional publications.
Background References:
  • Dorwart, M.R., (2008) J. Biol. Chem. 283 (13), 8711-8722.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SLC26A3.
NCBI Gene ID #:
1811
NCBI Official Name:
solute carrier family 26 (anion exchanger), member 3
NCBI Official Symbol:
SLC26A3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
84 kDa
Protein Accession #:
NP_000102
Protein GI Number:
4557535
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Transcription ,Membrane
Swissprot #:
P40879
User NOte:
Optimal dilutions for each application to be determined by the researcher.