ProSci

SCN5A Antibody

Product Code:
 
PSI-28-312
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Canine (dog)
  • Fish
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
 
For short periods of storage (days) store at 4˚C. For longer periods of storage, store SCN5A antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
1 / 1
Antibody used in WB on Human SW620 at 0.2-1 ug/ml.
❮❯

Antibody used in WB on Human SW620 at 0.2-1 ug/ml.

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PSI-28-312-100ul100ul£662.00
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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Additional Names:
SCN5A, CDCD2, CMD1E, CMPD2, HB1, HB2, HH1, IVF, LQT3, Nav1.5, SSS1, VF1, HBBD, ICCD, PFHB1
Application Note:
SCN5A antibody can be used for detection of SCN5A by ELISA at 1:312500. SCN5A antibody can be used for detection of SCN5A by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
SCN5A is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. The protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram.The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. The encoded protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in two transcript variants encoding separate isoforms which differ by a single amino acid. Mutation nomenclature has been assigned with respect to the longer isoform.
Background References:
  • Shah, V.N., (2006) Proc. Natl. Acad. Sci. U.S.A. 103 (10), 3592-3597.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SCN5A.
NCBI Gene ID #:
6331
NCBI Official Name:
sodium channel, voltage-gated, type V, alpha subunit
NCBI Official Symbol:
SCN5A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
222 kDa, 227 kDa, 36 kDa
Protein Accession #:
NP_000326
Protein GI Number:
30089970
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Membrane ,Cancer
Swissprot #:
Q8IZC9
User NOte:
Optimal dilutions for each application to be determined by the researcher.