ProSci

Melanoma-associated antigen D1 Antibody

Product Code:
 
PSI-79-631
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Storage:
 
Store antibody at -20˚C for up to one year.
1 / 1
Western blot analysis of lysed extracts from PC12 cells using Melanoma-associated antigen D1 Antibody.
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Western blot analysis of lysed extracts from PC12 cells using Melanoma-associated antigen D1 Antibody.

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PSI-79-631-0.1mg0.1mg£481.00
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Further Information

Additional Names:
NRAGE, Dlixin, Dlxin1, Dlxin-1, MAGE-D1, mFLJ00163, DXBwg1492e, 2810433C11Rik, 5430405L04Rik, MAGED1
Application Note:
Western Blot: 1:500~1:1000
Background:
Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds p75NTR and antagonizes its association with TrkA, inhibits cell cycle progression, and facilitates p75NTR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate p53 transcriptional activity and inhibit cell proliferation. Enhances p53 phosphorylation and accumulation.
Background References:
  • Zhao Z, et al. (2002) Sci China C Life Sci. 45 (4): 412-20. Shen WG, et al. (2007) Cell Commun Adhes. 14 (1): 21-31. Cheresh DA, et al. (1984) J Biol Chem. 259 (12): 7453-9.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Melanoma-associated antigen D1 antibodyPeptide with sequence C-EAEARAEARNRMGIGDE derived from Mouse Melanoma-associated antigen D1.
NCBI Gene ID #:
94275
NCBI Official Name:
melanoma antigen, family D, 1
NCBI Official Symbol:
Maged1
NCBI Organism:
Peptide with sequence C-EAEARAEARNRMGIGDE derived from Mouse Melanoma-associated antigen D1.
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
95 kDa
Protein Accession #:
NP_062765.1
Protein GI Number:
9789935
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Apoptosis,Cancer
SPECIFICITY:
This antibody detects endogenous level of total Melanoma-associated antigen D1 protein.
Swissprot #:
Q9QYH6