ProSci

IKK-beta Antibody

Product Code:
 
PSI-79-613
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Western Blot (WB)
Storage:
 
Store antibody at -20˚C for up to one year.
1 / 2
Western blot analysis of lysed extracts from MDA cells using IKK-β (Ab-199).
2 / 2
Immunofluorescence staining of methanol-fixed HeLa cells using IKK-β (Ab-199).
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Western blot analysis of lysed extracts from MDA cells using IKK-β (Ab-199).
Immunofluorescence staining of methanol-fixed HeLa cells using IKK-β (Ab-199).

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PSI-79-613-0.1mg0.1mg£481.00
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Further Information

Additional Names:
IKK2, IKKB, IMD15, NFKBIKB, IKK-beta, I-kappa-B kinase 2, I-kappa-B-kinase beta, IKK2, IkBKB
Application Note:
Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200
Background:
Acts as part of the IKK complex in the conventional pathway of NF-κ-B activation and phosphorylates inhibitors of NF-κ-B thus leading to the dissociation of the inhibitor/NF-κ-B complex and ultimately the degradation of the inhibitor. Also phosphorylates NCOA3.
Background References:
  • Chen RA, et al. PLoS Pathog. 2008 Feb 8;4 (2): e22Yen CJ, et al. Cancer Res. 2008 Apr 15;68 (8): 2632-40
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
IKK-beta (Ab-199) antibody was raised against a peptide sequence around aa.197~201 (Q-K-Y-T-V) derived from Human IKK-β.
NCBI Gene ID #:
3551
NCBI Official Name:
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
NCBI Official Symbol:
IKBKB
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
87 kDa
Protein Accession #:
NP_001547.1
Protein GI Number:
41352712
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Other
SPECIFICITY:
This antibody detects endogenous level of total IKK-βprotein.
Swissprot #:
O14920