ProSci

H2B Antibody

Product Code:
 
PSI-79-638
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Storage:
 
Store antibody at -20˚C for up to one year.
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Western blot analysis of lysed extracts from HeLa and 293 cells using H2B Antibody.
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Western blot analysis of lysed extracts from HeLa and 293 cells using H2B Antibody.

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PSI-79-638-0.1mg0.1mg£481.00
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Further Information

Additional Names:
H2B, H2BQ, GL105, H2B.1, H2BFQ, H2BGL105
Application Note:
Western Blot: 1:500~1:1000
Background:
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Background References:
  • Borchert GM, et al. (2010) PLoS One. 5 (7): e11641. Pennini ME, et al. (2010) PLoS Pathog. 6 (7): e1000995. Lu C, et al. (2010) Sci China Life Sci. 53 (6): 663-8.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
H2B antibody was raised against a peptide sequence around aa.41~45 (Y-V-Y-K-V) derived from Human H2B.
NCBI Gene ID #:
8349
NCBI Official Name:
histone cluster 2, H2be
NCBI Official Symbol:
HIST2H2BE
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
14 kDa
Protein Accession #:
NP_003519.1
Protein GI Number:
4504277
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Other
SPECIFICITY:
This antibody detects endogenous level of total H2B protein.
Swissprot #:
P33778