ProSci

Fibrillarin Antibody

Product Code:
 
PSI-79-685
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Storage:
 
Store antibody at -20˚C for up to one year.
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Western blot analysis of extract from 293, HeLa cells using Fibrillarin Antibody.
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Western blot analysis of extract from 293, HeLa cells using Fibrillarin Antibody.

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PSI-79-685-0.1mg0.1mg£481.00
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Further Information

Additional Names:
FIB, FLRN, RNU3IP1, FBL, FIB
Application Note:
Western Blot: 1:500~1:1000
Background:
Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.
Background References:
  • Lischwe M. A., Ochs R. L., Reddy R., Cook R. G., Yeoman L. C., Tan E. M., Reichlin M., Busch H. J. Biol. Chem. 260:14304-14310 (1985) Yanagida M., Hayano T., Yamauchi Y., Shinkawa T., Natsume T., Isobe T., Takahashi N. J. Biol. Chem. 279:1607-1614 (2004) Wang Y., Liu J., Zhao H., Lue W., Zhao J., Yang L., Li N., Du X., Ke Y. Biochim. Biophys. Acta 1773:863-868 (2007)
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Fibrillarin antibody was raised against a peptide sequence around aa.297~301 ( L-T-L-E-P) derived from Human Fibrillarin.
NCBI Gene ID #:
2091
NCBI Official Name:
fibrillarin
NCBI Official Symbol:
FBL
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
37 kDa
Protein Accession #:
NP_001427.2
Protein GI Number:
12056465
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Stem Cell
SPECIFICITY:
This antibody detects endogenous level of total Fibrillarin protein.
Swissprot #:
P22087