Chemodex

Tetramethylrhodamine-5-maleimide

Product Code:
 
CDX-T0029
Product Group:
 
Dyes, Stains, and Probes
Supplier:
 
Chemodex
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
-20 °C
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Chemical Structure
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Chemical Structure

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CDX-T0029-M0011 mg£109.00
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CDX-T0029-M02525 mg£784.00
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Further Information

Alternate Names/Synonyms:
5-TAMRA Maleimide; TMR-5 Malemide
Appearance:
Pink solid.
CAS:
174568-67-3
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C28H23N3O5/c1-29(2)16-5-9-20-23(14-16)36-24-15-17(30(3)4)6-10-21(24)27(20)19-8-7-18(13-22(19)28(34)35)31-25(32)11-12-26(31)33/h5-15H,1-4H3
InChiKey:
GXCPCIODYFPPQV-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 174568-67-3. Formula: C28H23N3O5. MW: 481.5. Synthetic. Labeling reagent for protein thiols for cytofluorescence.
MDL:
MFCD31010429
Molecular Formula:
C28H23N3O5
Molecular Weight:
481.5
Package Type:
Vial
Product Description:
The purified single isomer of tetramethylrhodamine-5 (and 6)-maleimide mixed isomers. Thiol-reactive fluorescent probe, widely used for modifications of peptides and proteins. It is preferred for some complicated biological applications where reproducibility is more critical than material cost since the minor positional difference between the 5-isomer and 6-isomer might significantly affect some biological properties of the underlying conjugates. Spectral data: lambdaex=540nm, lambdaem=567nm.
Purity:
>85% (HPLC)
SMILES:
CN(C)C1=CC=C2C(OC3=CC(C=CC3=C2C2=CC=C(C=C2C([O-])=O)N2C(=O)C=CC2=O)=[N+](C)C)=C1
Solubility Chemicals:
Soluble in methanol, DMSO.
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

(1) A. Pompella et al.; Meths. Mol. Biol. 196, 305 (2002)