Chemodex

3,3'-Dipropylthiacarbocyanine iodide

Product Code:
 
CDX-D0007
Product Group:
 
Dyes, Stains, and Probes
Supplier:
 
Chemodex
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
-20 °C
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Chemical Structure
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Chemical Structure

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CDX-D0007-M250250 mg£89.00
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CDX-D0007-M500500 mg£132.00
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Further Information

Alternate Names/Synonyms:
DiSC(3)(3)
Appearance:
Solid.
CAS:
53336-12-2
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Protect from light and moisture.
Hazards:
H315, H319, H335
InChi:
InChI=1S/C23H25N2S2.HI/c1-3-16-24-18-10-5-7-12-20(18)26-22(24)14-9-15-23-25(17-4-2)19-11-6-8-13-21(19)27-23;/h5-15H,3-4,16-17H2,1-2H3;1H/q+1;/p-1
InChiKey:
JGTCEHAVVINOPG-UHFFFAOYSA-M
Long Description:
Chemical. CAS: 53336-12-2. Formula: C23H25IN2S2. MW: 520.49. Synthetic. Carbocyanine dyes, particularly thiacyanines such as DiSC3(3) can inhibit respiration and may therefore be relatively cytotoxic. 3,3'-dipropyl-thiadicarbocyanine iodide is sensitive to membrane potential, fluorescence response to depolarization depends on the staining concentration and detection method. Selected applications are: -Calcium channels and other ion transport systems -Mitochondrial activity -Neurons and brain tissue -Membrane potential in intact yeast cells
MDL:
MFCD00013340
Molecular Formula:
C23H25IN2S2
Molecular Weight:
520.49
Package Type:
Vial
Precautions:
P261, P305, P351, P338
Product Description:
Carbocyanine dyes, particularly thiacyanines such as DiSC3(3) can inhibit respiration and may therefore be relatively cytotoxic. 3,3'-dipropyl-thiadicarbocyanine iodide is sensitive to membrane potential, fluorescence response to depolarization depends on the staining concentration and detection method. Selected applications are: -Calcium channels and other ion transport systems -Mitochondrial activity -Neurons and brain tissue -Membrane potential in intact yeast cells
Purity:
>98% (NMR)
Signal word:
Warning
SMILES:
[I-].CCCN1C(SC2=C1C=CC=C2)=C/C=C/C1=[N+](CCC)C2=C(S1)C=CC=C2
Solubility Chemicals:
Soluble in methanol, DMSO or DMF.
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

(1) D. Gaskova et al.; Biochem. Biophys. Res. Comm. 354(3), 814 (2007) | (2) D. Gaskova et al.; Int. J. Biochem. Cell Biol. 34(8), 931 (2002) | (3) H. Amlal et al.; M. Bichara; J. Biol. Chem. 269, 21962 (1994) | (4) H.W. van Veen et al.; Biol. Chem. 269, 29509 (1994) | (5) L. Hunyady et al.; Am. J. Physiol. 266, C67 (1994)