ProSci

SGSM3 Antibody

Product Code:
 
PSI-7037
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Western Blot (WB)
1 / 2
Western blot analysis of SGSM3 in 293 cell lysate with SGSM3 antibody at (A) 1 and (B) 2 μg/mL.
2 / 2
Immunofluorescence of SGSM3 in 293 cells with SGSM3 antibody at 20 μg/mL.
❮❯

Western blot analysis of SGSM3 in 293 cell lysate with SGSM3 antibody at (A) 1 and (B) 2 μg/mL.
Immunofluorescence of SGSM3 in 293 cells with SGSM3 antibody at 20 μg/mL.

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CodeSizePrice
PSI-7037-0.02mg0.02mg£150.00
Quantity:
PSI-7037-0.1mg0.1mg£449.00
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Further Information

Additional Names:
SGSM3 Antibody: MAP, RUSC3, RUTBC3, RABGAP5, RabGAP-5, MAP, RABGAPLP, Small G protein signaling modulator 3, Merlin-associated protein, RabGAPLP
Application Note:
SGSM3 antibody can be used for detection of SGSM3 by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
SGSM3 Antibody: Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation.? A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. Little is known of the exact function of SGSM3.
Background References:
  • Bar-Sagi D and Hall A. Ras and Rho GTPases: a family reunion. Cell 2000; 103:227-38.
  • Colicelli J. Human ras superfamily proteins and related GTPases. Sci. STKE 2004; 250:RE13.
  • Yang H, Sasaki T, Minoshima S, et al. Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway. Genomics 2007; 90:249-60.
Buffer:
SGSM3 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat: (82%), Mouse: (82%), Bovine: (79%)
Immunogen:
SGSM3 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human SGSM3.

The immunogen is located within amino acids 30 - 80 of SGSM3.
NCBI Gene ID #:
27352
NCBI Official Name:
small G protein signaling modulator 3
NCBI Official Symbol:
SGSM3
NCBI Organism:
homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
82 kDa
Protein Accession #:
CAQ08933
Protein GI Number:
168985143
Purification:
SGSM3 Antibody is affinity chromatography purified via peptide column.
Research Area:
Signal Transduction
SPECIFICITY:
Multiple isoforms of SGSM3 are known to exist. SGSM3 antibody is predicted to not cross react with other SGSM family proteins.
Swissprot #:
Q96HU1
User NOte:
Optimal dilutions for each application to be determined by the researcher.