ProSci

FAM193B Antibody

Product Code:
 
PSI-6941
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Western Blot (WB)
1 / 2
Western blot analysis of FAM193B in Jurkat cell lysate with FAM193B antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
2 / 2
Immunofluorescence of FAM193B in Jurkat cells with FAM193B antibody at 20 μg/mL.
❮❯

Western blot analysis of FAM193B in Jurkat cell lysate with FAM193B antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
Immunofluorescence of FAM193B in Jurkat cells with FAM193B antibody at 20 μg/mL.

No additional charges, what you see is what you pay! *

CodeSizePrice
PSI-6941-0.02mg0.02mg£150.00
Quantity:
PSI-6941-0.1mg0.1mg£449.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 14-21 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Related Products
  • Show All

Further Information

Additional Names:
FAM193B Antibody: IRIZIO, KIAA1931, Protein FAM193B
Application Note:
FAM193B antibody can be used for detection of FAM193B by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Background:
FAM193B Antibody: FAM193B, also known as IRIZIO, was initially identified as a protein that is upregulated in alveolar rhabdomyosarcoma (ARMS), a type of fast-growing tumor characterized by chromosomal translocations fusing the PAX3 or PAX7 gene with that of FOXO1. It has been suggested that, in addition to the PAX3-FOXO1 gene fusion, disruption of the Rb and p53 pathways is required for full ARMS tumorigenesis. In PAX3-FOXO1-expressing primary mouse fibroblasts that possessed a defective p53 pathway, FAM193B expression enabled the tumorigenic transformation, suggesting that FAM193B may contribute to rhabdomyosarcomagenesis in humans.
Background References:
  • Picchione F, Pritchard C, Lagutina I, et al. IRIZIO: a novel gene cooperating with PAX3-FOXO1 in alveolar rhabdomyosarcoma (ARMS). Carcinogenesis 2011; 32:452-62.
  • Linardic CM. PAX3-FOXO1 fusion gene in rhabdomyosarcoma. Cancer Lett. 2008; 270:10-8.
Buffer:
FAM193B Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (100%), Mouse: (81%)
Immunogen:
FAM193B antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human FAM193B.

The immunogen is located within amino acids 120 - 170 of FAM193B.
NCBI Gene ID #:
54540
NCBI Official Name:
family with sequence similarity 193, member B
NCBI Official Symbol:
FAM193B
NCBI Organism:
homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
99 kDa
Protein Accession #:
Q96PV7
Protein GI Number:
205831282
Purification:
FAM193B Antibody is affinity chromatography purified via peptide column.
Research Area:
Cancer,Cell Cycle
SPECIFICITY:
At least two isoforms of FAM193B are known to exist; this antibody will detect both isoforms.
Swissprot #:
Q96PV7
User NOte:
Optimal dilutions for each application to be determined by the researcher.