ProSci

INCA1 Antibody

Product Code:
 
PSI-5531
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Western Blot (WB)
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Western blot analysis of FAM212A in EL4 cell lysate with FAM212A antibody at (A) 1 and (B) 2 μg/ml.
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Western blot analysis of FAM212A in EL4 cell lysate with FAM212A antibody at (A) 1 and (B) 2 μg/ml.

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CodeSizePrice
PSI-5531-0.02mg0.02mg£150.00
Quantity:
PSI-5531-0.1mg0.1mg£449.00
Quantity:
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Further Information

Additional Names:
Family with sequence similarity 212 member A, INKA1, C3orf54
Application Note:
FAM212A antibody can be used for detection of FAM212A by Western blot at 1 - 2 μg/ml.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.
Background:
FAM212A, initially identified as INCA (induced in neural crest by AP-2alpha) in xenopus, is expressed primarily in neural crest cells and their derivatives (1). FAM212A can associate with the P21-kinase protein PAK4 and this association modulates cytoskeletal dynamics (1). In mammals, FAM212A is thought to play a role in neural tube closure; a significant fraction of FAM212A-null mice exhibited exencephaly (2).
Background References:
  • Luo T, Xu Y, Hoffman TL, et al. Inca: a novel p21-activated kinase-associated protein required for cranial neural crest development. Dev. 2007; 134:1279-89.
  • Reid BS, Sargent TD, and Willams T. Generation and characterization of a novel neural crest marker allele, Inka1-LacZ, reveals a role for Inka1 in mouse neural tube closure. Dev. Dyn. 2010; 239:1188-96.
Buffer:
FAM212A antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
FAM212A antibody was raised against a 15 amino acid peptide near the carboxy terminus of human FAM212A.

The immunogen is located within the last 50 amino acids of FAM212A.
NCBI Gene ID #:
389119
NCBI Official Name:
Family with sequence similarity 212 member A
NCBI Official Symbol:
FAM212A
NCBI Organism:
homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Predicted: 32 kDa

Observed: 33 kDa
Protein Accession #:
NP_976248
Protein GI Number:
42766424
Purification:
FAM212A antibody is affinity chromatography purified via peptide column.
Research Area:
Stem Cell,Neuroscience
SPECIFICITY:
FAM212A antibody is human and mouse . At least two isoforms of FAM212A are known to exist; this antibody will recognize both isoforms.
Swissprot #:
Q96EL1
User NOte:
Optimal dilutions for each application to be determined by the researcher.