ProSci

ZBED3 Antibody

Product Code:
 
PSI-5123
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
1 / 1
Western blot analysis of ZBED3 in A-20 cell lysate with ZBED3 antibody at 1 μg/ml.
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Western blot analysis of ZBED3 in A-20 cell lysate with ZBED3 antibody at 1 μg/ml.

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CodeSizePrice
PSI-5123-0.02mg0.02mg£150.00
Quantity:
PSI-5123-0.1mg0.1mg£449.00
Quantity:
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Further Information

Additional Names:
ZBED3 Antibody: Zinc finger BED domain-containing protein 3, Axin-interacting protein
Application Note:
ZBED3 antibody can be used for detection of ZBED3 by Western blot at 1 - 2 μg/mL. Despite its predicted molecular weight, ZBED3 often migrates at a higher position in SDS-PAGE.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.
Background:
ZBED3 Antibody: Axin is a key modulator of the Wnt/beta-catenin pathway and acts as a scaffold protein in phosphorylating and degrading cytoplasmic beta-catenin. ZBED3, a member of the Zinc finger BED-type domain containing superfamily, has been recently identified as an Axin-interacting protein and has been suggested to modulate the Wnt/beta-catenin signaling pathway. RNA interference (RNAi) experiments targeting ZBED3 RNA attenuated Wnt-induced beta-catenin accumulation, lymphoid enhancer binding factor-1-dependent luciferase reporter activity, and Wnt gene expression.
Background References:
  • Chen T, Li M, Ding Y, et al. Identification of Zinc-finger BED domain containing 3 (Zbed3) as a novel axin-interacting protein that activates Wnt/b-catenin signaling. J. Biol. Chem.2009; 284:6683-9.
Buffer:
ZBED3 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
ZBED3 antibody was raised against a 17 amino acid synthetic peptide from near the amino terminus of human ZBED3.

The immunogen is located within the first 50 amino acids of ZBED3.
NCBI Gene ID #:
84327
NCBI Official Name:
zinc finger, BED-type containing 3
NCBI Official Symbol:
ZBED3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Predicted: 26 kDa

Observed: 28 kDa
Protein Accession #:
NP_115743
Protein GI Number:
14150185
Purification:
ZBED3 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis
SPECIFICITY:
This antibody is predicted to have no cross-reactivity to ZBED1 or ZBED2.
Swissprot #:
Q96IU2
User NOte:
Optimal dilutions for each application to be determined by the researcher.