ProSci

STEAP4 Antibody

Product Code:
 
PSI-4313
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
1 / 1
Western blot analysis of STEAP4 in rat liver tissue lysate with STEAP4 antibody at (A) 0.5 and (B) 1 μg/mL.
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Western blot analysis of STEAP4 in rat liver tissue lysate with STEAP4 antibody at (A) 0.5 and (B) 1 μg/mL.

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CodeSizePrice
PSI-4313-0.02mg0.02mg£150.00
Quantity:
PSI-4313-0.1mg0.1mg£449.00
Quantity:
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Further Information

Additional Names:
STEAP4 Antibody: TIARP, STAMP2, TNFAIP9, Metalloreductase STEAP4, Six-transmembrane epithelial antigen of prostate 4
Application Note:
STEAP4 antibody can be used for detection of STEAP4 by Western blot at 0.5 - 1 μg/mL.

Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.
Background:
STEAP4 Antibody: The six-transmembrane epithelial antigen of prostate 4 (STEAP4) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP3), STEAP4 promotes both iron and copper reduction. STEAP4 is highly expressed in placenta, lung, heart and prostate tissues, and overexpressed in prostate cancer cells compared to normal prostate cells. Overexpression of STEAP4 in prostate cells significantly increases cell growth and colony formation, suggesting STEAP4 may have a role in cell proliferation and prostate cancer progression.
Background References:
  • Korkmaz CG, Korkmaz KS, Kurys P, et al. Molecular cloning and characterization of STAMP2, an androgen-regulated six transmembrane protein that is overexpressed in prostate cancer. Oncogene 2005; 24:4934-45.
  • Ohgami RS, Campagna DR, McDonald A, et al. The Steap proteins are metalloreductases. Blood2006; 108:1388-94.
Buffer:
STEAP4 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
STEAP4 antibody was raised against a 14 amino acid synthetic peptide from near the center of human STEAP4.

The immunogen is located within amino acids 210 - 260 of STEAP4.
NCBI Gene ID #:
79689
NCBI Official Name:
STEAP family member 4
NCBI Official Symbol:
STEAP4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
EAW76907
Protein GI Number:
119597313
Purification:
STEAP4 Antibody is affinity chromatography purified via peptide column.
Research Area:
Homeostasis,Cancer
SPECIFICITY:
At least two isoforms are known to exist for this protein. This STEAP4 antibody does not cross-react with other STEAP proteins.
Swissprot #:
Q687X5
User NOte:
Optimal dilutions for each application to be determined by the researcher.