ProSci

BAP29 Antibody

Product Code:
 
PSI-3669
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
1 / 1
Western blot analysis of Bap29 in human heart tissue lysate with Bap29 antibody at (A) 1 and (B) 2 μg/mL.
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Western blot analysis of Bap29 in human heart tissue lysate with Bap29 antibody at (A) 1 and (B) 2 μg/mL.

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CodeSizePrice
PSI-3669-0.02mg0.02mg£150.00
Quantity:
PSI-3669-0.1mg0.1mg£449.00
Quantity:
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Further Information

Additional Names:
BAP29 Antibody: BAP29, BAP29, B-cell receptor-associated protein 29, BCR-associated protein 29
Application Note:
Bap29 antibody can be used for the detection of Bap29 by Western blot at 1 - 2 μg/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Background:
BAP29 Antibody: Bap29 and the related protein Bap31 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family. These two proteins are highly homologous and can form homo- and heterodimers. Both Bap29 and Bap31 interact with membrane-bound immunoglobulins (mIgs), such as IgM and IgD, which with Ig-alpha/Ig-beta heterodimers form B cell antigen receptors. Binding of the Bap29/Bap31 heterodimer correlates with the ER retention of non-Ig-alpha/Ig-beta bound mIg complexes, suggesting that Bap29 and Bap31 may act as chaperones transmembrane regions of various proteins. Bap29 possesses multiple isoforms.
Background References:
  • Kim KM, Adachi T, Nielsen PJ, et al. Two new proteins preferentially associated with membrane immunoglobulin D. EMBO J.1994; 13:3793-800.
  • Ng F, Nguyen M, Kwan T, et al. p28 BAP31, a Bcl-2/Bcl-XL- and procaspase-8-associated protein the endoplasmic reticulum. J. Cell Biol.1997; 139:327-38.
  • Schamel WW, Kuppig S, Becker B, et al. A high-molecular-weight complex of membrane proteins BAP29/BAP31 is involved in the retention of membrane-bound IgD in the endoplasmic reticulum. Proc. Natl. Acad. Sci. USA2003; 100:9861-6.
Buffer:
BAP29 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
BAP29 antibody was raised against a 17 amino acid synthetic peptide from near the center of human Bap29 Bap29 antibody is specific for isoform a of Bap29.

The immunogen is located within amino acids 230 - 280 of BAP29.
NCBI Gene ID #:
55973
NCBI Official Name:
B-cell receptor-associated protein 29
NCBI Official Symbol:
BCAP29
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_001008405
Protein GI Number:
56549093
Purification:
BAP29 Antibody is affinity chromatography purified via peptide column.
Research Area:
Signal Transduction
Swissprot #:
Q9UHQ4
User NOte:
Optimal dilutions for each application to be determined by the researcher.