TargetMol

APE1-IN-1

Product Code:
 
TAR-T61487
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1

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CodeSizePrice
TAR-T61487-500mg500mg£1,674.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
APE1-IN-1 is a highly potent inhibitor of apurinic/apyrimidinic (AP) endonuclease 1 (APE1), which efficiently crosses the blood-brain barrier (BBB). With an IC50 value of 2 uM, APE1-IN-1 enhances the cytotoxicity of cancer cells when combined with alkylating agents such as Methylmethane sulfonate and Temozolomide [1].
CAS:
524708-03-0
Molecular Weight:
371.52
Purity:
0.98
SMILES:
O=C(NC=1SC2=C(C1C3=NC=4C=CC=CC4S3)CCN(C2)C(C)C)C