TargetMol

6-Hydroxypyridin-2(1H)-one hydrochloride

Product Code:
 
TAR-T4720
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T4720-200mg200mg£94.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T4720-1mL1 mL * 10 mM (in DMSO)£107.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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Further Information

Bioactivity:
2,6-Dihydroxypyridine hydrochloride is used as a reagent to synthesize uridine phosphorylase inhibitors that increase Uridine (Urd) (U829910) levels. Uridine is a promising biochemical modulator to reduce 5-fluorouracil (5-FU) toxicity without impairing its antitumor activity.
CAS:
10357-84-3
Molecular Weight:
147.56
Pathway:
Others|Metabolism
Purity:
0.98
SMILES:
Cl.Oc1cccc(O)n1
Target:
Endogenous Metabolite|Others

References

Renck D, et al. Design of novel potent inhibitors of human uridine phosphorylase-1: synthesis, inhibition studies, thermodynamics, and in vitro influence on 5-fluorouracil cytotoxicity. J Med Chem. 2013 Nov 14;56(21):8892-902.