TargetMol

Maraciclatide

Product Code:
 
TAR-TP2390
Product Group:
 
Peptides
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Maraciclatide is a radiopharmaceutical targeting αvβ3 integrin.
CAS:
489427-17-0
Molecular Weight:
1698.05
Purity:
0.98
SMILES:
[H][C@]12CSSC[C@]([H])(NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CSCC(=O)N[C@@H](CCCCNC(=O)CCCC(=O)NCCC(CCNC(C)(C)C(C)=NO)CCNC(C)(C)C(C)=NO)C(=O)N2)C(=O)NCCOCCOCCOCCNC(=O)COCC(N)=O |w:80.82,90.92|

References

O'Connor MK, Morrow MMB, Hunt KN, Boughey JC, Wahner-Roedler DL, Conners AL, Rhodes DJ, Hruska CB. Comparison of Tc-99m maraciclatide and Tc-99m sestamibi molecular breast imaging in patients with suspected breast cancer. EJNMMI Res. 2017 Dec;7(1):5. doi: 10.1186/s13550-017-0255-6. Epub 2017 Jan 14. PubMed PMID: 28091980; PubMed Central PMCID: PMC5237435. Cook GJR, Azad GK, Taylor BP, Lee E, Morrison MS, Hughes S, Morris S, Rudman S, Chowdhury S, Goh V. Imaging ?(v)?(3) integrin expression in skeletal metastases with (99m)Tc-maraciclatide single-photon emission computed tomography: detection and therapy response assessment. Eur J Nucl Med Mol Imaging. 2018 Jun;45(6):898-903. doi: 10.1007/s00259-017-3926-7. Epub 2018 Feb 2. PubMed PMID: 29396636; PubMed Central PMCID: PMC5915496. Vancraeynest D, Roelants V, Bouzin C, Hanin FX, Walrand S, Bol V, Bol A, Pouleur AC, Pasquet A, Gerber B, Lesnik P, Huby T, Jamar F, Vanoverschelde JL. ?V?3 integrin-targeted microSPECT/CT imaging of inflamed atherosclerotic plaques in mice. EJNMMI Res. 2016 Dec;6(1):29. doi: 10.1186/s13550-016-0184-9. Epub 2016 Mar 24. PubMed PMID: 27009066; PubMed Central PMCID: PMC4805679.