TargetMol

Protein kinase inhibitor peptide

Product Code:
 
TAR-TP2349
Product Group:
 
Peptides
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-TP2349-500mg500mgEnquire
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Further Information

Bioactivity:
Protein kinase inhibitor peptide matches the inhibitory domain of the heat-stable protein kinase inhibitor.
CAS:
128022-93-5
Molecular Weight:
1970.15
Purity:
0.98
SMILES:
[C@H](CC1=CC=CC=C1)(C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]([C@H](CC)C)C(O)=O)=O)C)=O)CC(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=O)[C@@H](C)O)=O)CCCNC(=N)N)=O)=O)CO)=O)C)=O)[C@H](CC)C)=O)NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)NC([C@@H](NC([C@H]([C@@H](C)O)N)=O)[C@@H](C)O)=O)=O)C)=O)CC(O)=O)=O

References

Dalton GD, Dewey WL. Protein kinase inhibitor peptide (PKI): a family of endogenous neuropeptides that modulate neuronal cAMP-dependent protein kinase function. Neuropeptides. 2006 Feb;40(1):23-34. Epub 2006 Jan 26. Review. PubMed PMID: 16442618. Taffs RE, Sitkovsky MV. Modulation of the effector functions of cytolytic T-lymphocytes with synthetic peptide inhibitors of protein kinases. J Pharm Sci. 1992 Jan;81(1):37-44. PubMed PMID: 1619567. Glass DB, Feller MJ, Levin LR, Walsh DA. Structural basis for the low affinities of yeast cAMP-dependent and mammalian cGMP-dependent protein kinases for protein kinase inhibitor peptides. Biochemistry. 1992 Feb 18;31(6):1728-34. PubMed PMID: 1310617. Olah GA, Mitchell RD, Sosnick TR, Walsh DA, Trewhella J. Solution structure of the cAMP-dependent protein kinase catalytic subunit and its contraction upon binding the protein kinase inhibitor peptide. Biochemistry. 1993 Apr 13;32(14):3649-57. PubMed PMID: 8385485.