TargetMol

Peptide 78

Product Code:
 
TAR-TP2347
Product Group:
 
Peptides
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Peptide 78 is identical to peptide 74 except that serine replaces cysteine. It does not inhibit 72-kDa type IV collagenase.
CAS:
132116-62-2
Molecular Weight:
1542.74
Purity:
0.98
SMILES:
CSCC[C@H](NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(O)=O

References

Zats GM, Kovaliov M, Albeck A, Shatzmiller S. Antimicrobial benzodiazepine-based short cationic peptidomimetics. J Pept Sci. 2015 Jun;21(6):512-9. doi: 10.1002/psc.2771. Epub 2015 Mar 25. PubMed PMID: 25807936. Yang T, Wang S, Zheng Q, Wang L, Li Q, Wei M, Du Z, Fan Y. Increased plasma levels of epithelial neutrophil-activating peptide 78/CXCL5 during the remission of Neuromyelitis optica. BMC Neurol. 2016 Jul 11;16:96. doi: 10.1186/s12883-016-0622-3. PubMed PMID: 27401736; PubMed Central PMCID: PMC4940958. Buer BC, Chugh J, Al-Hashimi HM, Marsh EN. Using fluorine nuclear magnetic resonance to probe the interaction of membrane-active peptides with the lipid bilayer. Biochemistry. 2010 Jul 13;49(27):5760-5. doi: 10.1021/bi100605e. PubMed PMID: 20527804. Wang H, Zhao J, Xue G, Wang J, Wu J, Wang D, Dong L. Regulatory effect of cytokine-induced neutrophil chemoattractant, epithelial neutrophil-activating peptide 78 and pyrrolidine dithiocarbamate on pulmonary neutrophil aggregation mediated by nuclear factor-?B in lipopolysaccharide-induced acute respiratory distress syndrome mice. Exp Ther Med. 2016 Sep;12(3):1785-1794. Epub 2016 Jul 13. PubMed PMID: 27602092; PubMed Central PMCID: PMC4998193.