TargetMol

TAT-DEF-Elk-1 TFA (1220751-16-5 free base)

Product Code:
 
TAR-TP2157L
Product Group:
 
Peptides
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
 

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TAR-TP2157L-100mg100mgEnquire
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TAR-TP2157L-500mg500mgEnquire
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Further Information

Bioactivity:
TAT-DEF-Elk-1 TFA is a cell-penetrating peptide Elk-1 inhibitor, mimics and specifically interferes with the DEF domain of Elk-1. TAT-DEF-Elk-1 blocks Elk-1 phosphorylation and prevents Elk-1 nuclear translocation without interfering with ERK nor MSK1 activation. TAT-DEF-Elk-1 is a useful tool to analyze the role of Elk-1 in this process during the development of neuronal plasticity
CAS:
TP2157L
Molecular Weight:
3675.09
Purity:
0.98

References

Lavaur J, et al. A TAT-DEF-Elk-1 peptide regulates the cytonuclear trafficking of Elk-1 and controls cytoskeleton dynamics.J Neurosci.?2007 Dec 26;27(52):14448-58. Apazoglou K, et al. Antidepressive?effects?of?targeting?ELK-1?signal transduction.Nat Med.?2018 May;24(5):591-597.