TargetMol

2',3'-cGAMP-C2-PPA

Product Code:
 
TAR-T40224
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1

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TAR-T40224-100mg100mgEnquire
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TAR-T40224-500mg500mgEnquire
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This product comes from: United States.
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Further Information

Bioactivity:
2',3'-cGAMP-C2-PPA (45) is a cyclic di-nucleotide that acts as a STING agonist (US20210015941A1). It is a drug-linker conjugate for antibody-drug conjugates (ADC) used in the targeted treatment of cancer.
CAS:
2586047-11-0
Molecular Weight:
850.71
Purity:
0.98
SMILES:
[H][C@@]12COP(O)(=O)O[C@@]3([H])[C@@H](O)[C@@H](O[C@]3([H])COP(O)(=O)O[C@]([H])(C1CCSSC(C)CCC(O)=O)[C@@H](O2)n1cnc2c1[nH]c(N)nc2=O)n1cnc2c(N)ncnc12

References

Chen Z, et, al. Antibody-sting agonist conjugates and their use in immunotherapy. US20210015941A1.