TargetMol

(S,R,S)-AHPC-C6-NH2 hydrochloride

Product Code:
 
TAR-T39898
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
(S,R,S)-AHPC-C6-NH2 hydrochloride (also known as VH032-C6-NH2 hydrochloride) is a synthetic E3 ligase ligand-linker conjugate. It combines the VH032-based VHL ligand with a linker designed for AKT PROTAC degrader applications. (S,R,S)-AHPC-C6-NH2 hydrochloride also referred to as XF038-161A or example 6, was isolated from patent WO2019173516A1.
CAS:
2360522-76-3
Molecular Weight:
594.21
Purity:
0.98
SMILES:
Cl.Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCN)C(C)(C)C)cc1 |@@:34|

References

Jian Jin, et al. Serine threonine kinase (akt) degradation / disruption compounds and methods of use. Patent WO2019173516A1.