TargetMol

Cyclooctyne-O-amido-PEG2-PFP ester

Product Code:
 
TAR-T39539
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Cyclooctyne-O-amido-PEG2-PFP ester is a two-unit polyethylene glycol (PEG) linker incorporated into antibody-drug conjugates (ADCs). It is a non-cleavable linker utilized in the synthesis of ADCs.
CAS:
2101206-61-3
Molecular Weight:
507.454
Purity:
0.98
SMILES:
Fc1c(F)c(F)c(OC(=O)CCOCCOCCNC(=O)COC2CCCCCC#C2)c(F)c1F

References

Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.