TargetMol

Tryptophyl adenylate

Product Code:
 
TAR-T34961
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Tryptophyl adenylate is a bioactive chemical.
CAS:
31528-64-0
Molecular Weight:
533.438
Purity:
0.98
SMILES:
N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12

References

Mazat JP, Merle M, Graves PV, Merault G, Gandar JC, Labouesse B. Kinetic anticooperativity in pre-steady-state formation of tryptophanyl adenylate by tryptophanyl-tRNA synthetase from beef pancreas. A consequence of the tryptophan anticooperative binding. Eur J Biochem. 1982 Nov 15;128(2-3):389-98. PubMed PMID: 7151786. Merault G, Labouesse J, Graves PV, Labouesse B. Kinetics of formation of tryptophanyl-adenylate by tryptophanyl-tRNA synthetase from beef pancreas. FEBS Lett. 1981 Jan 26;123(2):165-8. PubMed PMID: 6112162. Merle M, Trezeguet V, Graves PV, Andrews D, Muench KH, Labouesse B. Tryptophanyl adenylate formation by tryptophanyl-tRNA synthetase from Escherichia coli. Biochemistry. 1986 Mar 11;25(5):1115-23. PubMed PMID: 3516215. Koh CY, Kim JE, Napoli AJ, Verlinde CL, Fan E, Buckner FS, Van Voorhis WC, Hol WG. Crystal structures of Plasmodium falciparum cytosolic tryptophanyl-tRNA synthetase and its potential as a target for structure-guided drug design. Mol Biochem Parasitol. 2013 May;189(1-2):26-32. doi: 10.1016/j.molbiopara.2013.04.007. Epub 2013 May 7. PubMed PMID: 23665145; PubMed Central PMCID: PMC3680109.