TargetMol

Lysylcysteine

Product Code:
 
TAR-T33088
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T33088-100mg100mgEnquire
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TAR-T33088-500mg500mgEnquire
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Further Information

Bioactivity:
Lysylcysteine is a dipeptide composed of lysine and cysteine. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis. This dipeptide has not yet been identified in human tissues or biofluids and so it is classified as an 'Expected' metabolite.
CAS:
106325-92-2
Molecular Weight:
249.33
Purity:
0.98
SMILES:
[C@@H](NC([C@H](CCCCN)N)=O)(C(O)=O)CS

References

Dong L, Li C, Locuson C, Chen S, Qian MG. A Two-Step Immunocapture LC/MS/MS Assay for Plasma Stability and Payload Migration Assessment of Cysteine-Maleimide-Based Antibody Drug Conjugates. Anal Chem. 2018 May 15;90(10):5989-5994. doi: 10.1021/acs.analchem.8b00694. Epub 2018 Apr 24. PubMed PMID: 29688004. Drev D, Bileck A, Erdem ZN, Mohr T, Timelthaler G, Beer A, Gerner C, Marian B. Proteomic profiling identifies markers for inflammation-related tumor-fibroblast interaction. Clin Proteomics. 2017 Oct 6;14:33. doi: 10.1186/s12014-017-9168-7. eCollection 2017. PubMed PMID: 29176937; PubMed Central PMCID: PMC5689177. Qiu Q, Zhang F, Wu J, Xu N, Liang M. Gingipains disrupt F-actin and cause osteoblast apoptosis via integrin ?1. J Periodontal Res. 2018 May 18. doi: 10.1111/jre.12563. [Epub ahead of print] PubMed PMID: 29777544. Davidson VL. Protein-Derived Cofactors Revisited: Empowering Amino Acid Residues with New Functions. Biochemistry. 2018 Jun 5;57(22):3115-3125. doi: 10.1021/acs.biochem.8b00123. Epub 2018 Mar 6. PubMed PMID: 29498828; PubMed Central PMCID: PMC5988959.