TargetMol

Dihydrobetulinic acid

Product Code:
 
TAR-T31466
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Dihydrobetulinic acid is a bioactive chemical.
CAS:
25488-53-3
Formula:
C30H50O3
Molecular Weight:
458.727
Purity:
0.98
SMILES:
[H][C@]12C(CC[C@@]1(CC[C@]1(C)[C@]2([H])CC[C@]2([H])[C@@]3(C)CC[C@H](O)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O)C(C)C |@@:34|

References

Borkova L, Jasikova L, Rehulka J, Frisonsova K, Urban M, Frydrych I, Popa I, Hajduch M, Dickinson NJ, Vlk M, Dzubak P, Sarek J. Synthesis of cytotoxic 2,2-difluoroderivatives of dihydrobetulinic acid and allobetulin and study of their impact on cancer cells. Eur J Med Chem. 2015;96:482-90. doi: 10.1016/j.ejmech.2015.03.068. Epub 2015 Apr 1. PubMed PMID: 25942059. Sengupta T, Mukherjee M, Das A, Mandal C, Das R, Mukherjee T, Majumder HK. Characterization of the ATPase activity of topoisomerase II from Leishmania donovani and identification of residues conferring resistance to etoposide. Biochem J. 2005 Sep 1;390(Pt 2):419-26. PubMed PMID: 15901238; PubMed Central PMCID: PMC1198921. Kashiwada Y, Sekiya M, Ikeshiro Y, Fujioka T, Kilgore NR, Wild CT, Allaway GP, Lee KH. 3-O-Glutaryl-dihydrobetulin and related monoacyl derivatives as potent anti-HIV agents. Bioorg Med Chem Lett. 2004 Dec 6;14(23):5851-3. PubMed PMID: 15501054. Eignerova B, Tichy M, Krasulova J, Kvasnica M, Rarova L, Christova R, Urban M, Bednarczyk-Cwynar B, Hajduch M, Sarek J. Synthesis and antiproliferative properties of new hydrophilic esters of triterpenic acids. Eur J Med Chem. 2017 Nov 10;140:403-420. doi: 10.1016/j.ejmech.2017.09.041. Epub 2017 Sep 21. PubMed PMID: 28987603.