TargetMol

Dexibuprofen lysine

Product Code:
 
TAR-T31398
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
 

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TAR-T31398-100mg100mgEnquire
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TAR-T31398-500mg500mgEnquire
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Further Information

Bioactivity:
Dexibuprofen (S-ibuprofen) is a non-steroidal anti-inflammatory drug. Most ibuprofen preparations contain a racemic mixture of two isomers. Dexibuprofen as a cyclooxygenase inhibitor.
CAS:
113403-10-4
Molecular Weight:
352.47
Purity:
0.98
SMILES:
[H][C@@](C(O)=O)(C1=CC=C(C=C1)CC(C)C)C.N[C@H](C(O)=O)CCCCN

References

S?nchez-L?pez E, Ettcheto M, Egea MA, Espina M, Calpena AC, Folch J, Camins A, Garc?a ML. New potential strategies for Alzheimer's disease prevention: pegylated biodegradable dexibuprofen nanospheres administration to APPswe/PS1dE9. Nanomedicine. 2017 Apr;13(3):1171-1182. doi: 10.1016/j.nano.2016.12.003. Epub 2016 Dec 14. PubMed PMID: 27986603. Ashraf Z, Alamgeer, Rasool R, Hassan M, Ahsan H, Afzal S, Afzal K, Cho H, Kim SJ. Synthesis, Bioevaluation and Molecular Dynamic Simulation Studies of Dexibuprofen-Antioxidant Mutual Prodrugs. Int J Mol Sci. 2016 Dec 21;17(12). pii: E2151. doi: 10.3390/ijms17122151. PubMed PMID: 28009827; PubMed Central PMCID: PMC5187951. Arshad N, Zafran M, Ashraf Z, Perveen F. Synthesis, characterization of amide substituted dexibuprofen derivatives and their spectral, voltammetric and docking investigations for DNA binding interactions. J Photochem Photobiol B. 2017 Apr;169:134-147. doi: 10.1016/j.jphotobiol.2017.02.021. Epub 2017 Mar 3. PubMed PMID: 28319868. Gao Z, Cui F, Cao X, Wang D, Li X, Li T. Local infiltration of the surgical wounds with levobupivacaine, dexibuprofen, and norepinephrine to reduce postoperative pain: A randomized, vehicle-controlled, and preclinical study. Biomed Pharmacother. 2017 May 29;92:459-467. doi: 10.1016/j.biopha.2017.05.038. [Epub ahead of print] PubMed PMID: 28570980.