TargetMol

Desglymidodrine

Product Code:
 
TAR-T31388L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T31388L-100mg100mgEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T31388L-500mg500mgEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
Desglymidodrine is a Metabolite of midodrine (ST-1085). It is used in plasma of ascitic patients.
CAS:
3600-87-1
Formula:
C10H15NO3
Molecular Weight:
197.231
Purity:
0.98
SMILES:
COc1ccc(OC)c(c1)C(O)CN

References

Barth T, Aleu J, Pupo MT, Bonato PS, Collado IG. HPLC analysis of midodrine and desglymidodrine in culture medium: evaluation of static and shaken conditions on the biotransformation by fungi. J Chromatogr Sci. 2013 May-Jun;51(5):460-7. doi: 10.1093/chromsci/bms163. Epub 2012 Oct 9. PubMed PMID: 23051063. Patel DP, Nair S, Suhagia BN, Patel BM. A novel, sensitive and selective method of UPLC/MS-MS for rapid simultaneous determination of midodrine and its active metabolite desglymidodrine in human plasma: Application to support bioequivalence study in healthy human volunteers. J Pharm Biomed Anal. 2016 Nov 30;131:355-363. doi: 10.1016/j.jpba.2016.09.005. Epub 2016 Sep 5. PubMed PMID: 27639073. Ali AA, Al-Ghobashy MA, Farid SF, Kassem MA. Development and validation of LC-MS/MS assay for the determination of the prodrug Midodrine and its active metabolite Desglymidodrine in plasma of ascitic patients: Application to individualized therapy and comparative pharmacokinetics. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Jun 1;991:34-40. doi: 10.1016/j.jchromb.2015.03.032. Epub 2015 Apr 7. PubMed PMID: 25910235. Ali A, Farid S, Amin M, Kassem M, Al-Garem N, Al-Ghobashy M. Comparative Clinical Pharmacokinetics of Midodrine and Its Active Metabolite Desglymidodrine in Cirrhotic Patients with Tense Ascites Versus Healthy Volunteers. Clin Drug Investig. 2016 Feb;36(2):147-55. doi: 10.1007/s40261-015-0359-6. PubMed PMID: 26597181.